Formication and itchy skin in perimenopause are two of the most physically unsettling, least talked-about symptoms of this transition. Formication is the medical term for a very specific and very strange sensation — the feeling that insects, ants, or something unseen are crawling on or just beneath your skin, even though nothing is actually there. It often shows up alongside a more generalized, unexplained itchiness that seems to move around your body, flare at night, and defy every lotion you try. If you’ve caught yourself brushing at your arm for a bug that isn’t there, or scratching a spot that was never actually itchy to begin with, you are not losing your mind, and you are not alone. This has a real, documented hormonal mechanism, and by the end of this article you’ll understand exactly why it happens, how to tell it apart from something that needs a doctor’s attention, and what genuinely helps bring it down.
Let’s start with what almost nobody says clearly enough: this symptom is common, and it is deeply under-discussed, mostly because it sounds so alarming that women are afraid to even say it out loud. Telling a friend “I feel like something is crawling on my arm” invites a reaction of concern or disbelief that makes most women simply stop mentioning it. But formication and itchy skin in perimenopause are recognized, real, and traceable directly back to what’s happening with your hormones, your nerves, and your skin — not to your imagination, and not to anything crawling on you.
What’s Actually Happening: Formication and Itchy Skin in Perimenopause Explained
Here’s the sentence worth holding onto for the rest of this article, because it changes the entire emotional weight of the experience: your skin is not malfunctioning, and your nerves are not misfiring randomly. They are responding — in a traceable, physiologically consistent way — to a hormonal environment that is shifting faster than your nervous system and your skin have had time to adjust to. Formication and itchy skin in perimenopause are not a sign that something is crawling on you, and they are not a sign that your body is falling apart. They are a direct downstream consequence of estrogen’s decline, and once the mechanism is clear, the fear sitting on top of the sensation tends to loosen considerably.
Estrogen was doing more for your skin and nerves than you ever realized
For most of your adult life, estrogen has quietly supported far more than your reproductive system. Estrogen receptors exist throughout your skin — in the outer barrier layer, in the deeper dermis, and in the tiny nerve fibers that run just beneath the surface of your skin, called cutaneous nerve fibers. These nerve fibers are the ones responsible for transmitting sensations like touch, temperature, pressure, and yes, itch. Estrogen helps regulate how sensitive these nerve fibers are, how quickly they fire, and how efficiently your brain filters out the low-level background sensations your skin generates all day long, most of which you never consciously notice because your nervous system quietly discards them before they reach awareness.
Estrogen also plays a direct, structural role in your skin itself. It stimulates collagen production, supports the skin’s ability to hold onto moisture, and helps maintain the health of your skin’s outermost barrier — the thin layer that keeps water in and irritants out. As estrogen fluctuates and eventually declines during perimenopause, all of this steady, background support starts to waver, and your skin and nervous system are left adjusting to conditions they haven’t operated under before.
Your nerves start misreading normal signals
Think of your cutaneous nerve fibers as sensors constantly sending tiny signals up to your brain — most of which get filtered out before you ever notice them, the same way you don’t consciously feel your clothes touching your skin most of the time. Estrogen helps keep this filtering system calibrated. When estrogen drops, particularly when it drops sharply rather than gradually, this filtering system can become less efficient, and ordinary background signals that would normally be discarded start getting through instead, arriving in your conscious awareness as a tingle, a crawl, an itch, or a prickle that has no external cause at all.
This is the core mechanism behind formication: not a hallucination, not a delusion, but a genuine misfire in how your nervous system is interpreting entirely normal, low-level signals from your skin. Your nerves aren’t lying to you about the sensation — the crawling feeling is real, in the sense that your nervous system is genuinely producing it. What’s changed is simply that there’s no external trigger behind it anymore, because the trigger is internal and hormonal rather than something actually touching your skin.
The histamine connection nobody mentions
Here’s a piece of the puzzle that deserves far more attention than it gets: estrogen and histamine are deeply intertwined, and the relationship goes both directions. Estrogen influences how much histamine your body produces and how efficiently it’s broken down, while histamine itself can influence how much estrogen circulates. During perimenopause, as estrogen swings unpredictably, many women experience what’s sometimes called increased histamine reactivity — a state where histamine, the same chemical responsible for allergic reactions, itching, and hives, builds up more easily and gets cleared out more slowly than it used to.
Histamine is one of the body’s primary itch-signaling chemicals. When it’s elevated, it directly stimulates the nerve fibers in your skin associated with the sensation of itch, entirely independent of any actual skin condition, allergen, or bug. This is a major reason why itchy skin in perimenopause often shows up with no rash, no bite marks, no visible cause at all — because the itch is being generated internally, by a histamine and hormone imbalance, rather than by anything happening on the surface of your skin.
Dry skin, thinning skin, and irritated nerve endings
Alongside the nerve and histamine piece, there’s a more straightforward mechanical one: estrogen decline directly reduces collagen production and your skin’s ability to retain moisture, meaning your skin genuinely becomes drier and thinner during this transition, often faster than most women expect. Thinner, drier skin means the nerve endings sitting just beneath the surface are less cushioned and more exposed than they used to be, making them more easily triggered by things that never used to bother you at all — a wool sweater, a hot shower, even just the pressure of a waistband.
This dryness compounds the nerve-sensitivity piece described above. A nervous system that’s already misfiring low-level signals, combined with a skin barrier that’s thinner and less protective than it used to be, creates a kind of perfect storm where itch and crawling sensations become both more frequent and more intense than either factor would produce on its own.
Blood sugar swings and nerve sensitivity
There’s a connection here that rarely gets discussed outside specialist circles, and it matters more than most women realize: perimenopause tends to make your body somewhat more insulin resistant, even without any change to your diet. When blood sugar spikes and then crashes — after a sugary breakfast, a skipped meal, or caffeine on an empty stomach — your body releases a surge of adrenaline to bring blood sugar back up. Adrenaline doesn’t just affect your heart rate; it also increases the excitability of your peripheral nerves, the very same nerve fibers responsible for skin sensation. This is a genuinely underappreciated reason why formication and itchy skin in perimenopause often flare mid-afternoon, or wake women up in the middle of the night — timing that tracks blood sugar crashes far more closely than it tracks anything happening on the surface of the skin.
Magnesium, B12, and the mineral and nutrient piece
Peripheral nerve health depends heavily on adequate levels of specific nutrients, chiefly magnesium and vitamin B12, both of which are directly involved in maintaining the protective coating around your nerve fibers and in regulating how easily those nerves fire. Several things converging in perimenopause tend to push these levels lower than they used to be: hormonal shifts increase your body’s magnesium requirements, chronic stress depletes magnesium reserves faster, and B12 absorption naturally becomes somewhat less efficient with age, especially for women on certain medications or following a mostly plant-based diet. Even a mild deficiency in either nutrient — nowhere near severe enough to register as a red flag on a standard blood panel — can measurably increase nerve excitability, contributing directly to that crawling, tingling, prickling sensation so many women describe and struggle to explain.
The anxiety–sensation feedback loop
There’s a loop here worth naming directly, because it’s one of the most frustrating parts of this symptom: anxiety and heightened nervous system arousal directly increase how sensitive your skin’s nerve fibers are to sensation, in the same way it increases sensitivity to sound or light. A nervous system already on higher alert — which is extremely common during perimenopause, given the same estrogen swings driving mood and anxiety symptoms — becomes more likely to register a crawling or itching sensation, and more likely to fixate on it once it appears. And because formication is such an unsettling sensation in itself, noticing it tends to spike anxiety further, which then makes the nervous system even more reactive, which increases the odds of noticing the sensation again. This loop, on its own, can make a mild, intermittent symptom feel far more constant and severe than it actually is.
Why it often clusters at night or around your cycle
Many women notice formication and itchy skin in perimenopause aren’t evenly spread throughout the day or month — they cluster. Nighttime is an especially common pattern, for a few overlapping reasons: your body’s natural cortisol rhythm dips at night, which can unmask nerve sensitivity that daytime cortisol was partially suppressing; your skin loses more moisture overnight, particularly in a warm bedroom; and with fewer external distractions competing for your attention while you’re trying to fall asleep, your brain has far more bandwidth to notice sensations it would otherwise filter out during a busy day.
Cycle-related clustering shows up too. Many women notice symptoms intensify in the week or two before a period would have arrived, when progesterone — already declining overall — drops sharply from whatever level it reached that cycle. Others notice a spike around ovulation, when estrogen briefly surges before falling again. There’s no single universal pattern here; the value isn’t in memorizing someone else’s rule, it’s in noticing your own. Jotting down when a flare happens, alongside roughly where you are in your cycle, often reveals a clear pattern within a couple of months that makes an otherwise random-feeling symptom feel far more predictable.
Common Myths About Formication and Itchy Skin in Perimenopause
“If bugs aren’t actually there, this must be all in my head.” This is one of the most damaging misconceptions surrounding this symptom, and it deserves to be said plainly: formication is a well-documented physiological phenomenon with a real neurological and hormonal mechanism. The sensation is genuinely being produced by your nervous system — it isn’t a delusion, and it isn’t a sign of a psychiatric condition, even though it can feel deeply disorienting to experience.
“Itchy skin in perimenopause always means an allergy or a new skin condition.” Sometimes it does, and that possibility is worth ruling out, but a huge proportion of unexplained itching during this transition has no allergic or dermatological cause at all — it’s driven by hormone-related nerve sensitivity and histamine reactivity rather than anything on or reacting with your skin.
“If I just moisturize more, it’ll go away completely.” Moisturizing genuinely helps the mechanical, dryness-related piece of this symptom, but it doesn’t address the nerve sensitivity or histamine piece underneath it, which is why so many women find that even the richest lotion only takes the edge off rather than resolving the sensation entirely.
“This means something is seriously wrong with my nerves.” For the overwhelming majority of women experiencing this in the context of other perimenopausal symptoms, it doesn’t indicate nerve damage or a neurological disease — it reflects a temporary hormonal shift in nerve sensitivity that tends to ease considerably once hormones stabilize, whether that’s naturally or through targeted support.
Frequently Asked Questions
Is formication a real medical symptom, or am I imagining it? It’s genuinely real and well documented. Formication is a recognized symptom associated with hormonal fluctuation, certain nerve conditions, and some medications — the sensation itself is a legitimate neurological event, not something you’re imagining or exaggerating.
Why does my itchy skin have no rash, no bites, and nothing visible at all? This is actually a hallmark of hormonally-driven itch rather than a sign something’s being missed. Because the itch is generated internally — by nerve sensitivity and histamine activity rather than a skin-surface reaction — there’s often nothing to see, even though the sensation itself is completely real.
How long does formication in perimenopause usually last as a symptom? For most women, it comes and goes in episodes lasting anywhere from a few minutes to a few hours, often clustering at certain times of day or points in the cycle, rather than being constant. As hormones stabilize over the course of the transition, most women find it becomes noticeably less frequent.
Should I be worried this is a sign of a neurological condition? If it’s appearing alongside other clear perimenopause symptoms and there’s no accompanying weakness, numbness, or loss of coordination, it’s far more likely to be hormonally driven. That said, it’s genuinely worth a conversation with your doctor to rule out other causes, particularly if the sensation is new, severe, or doesn’t fit the pattern described here.
Can stress and anxiety make formication and itchy skin worse? Yes, significantly. Anxiety and nervous system arousal directly increase nerve sensitivity, and because this symptom is unsettling in itself, it tends to raise anxiety further, creating a loop where each part feeds the other. Calming your nervous system is one of the most effective tools you have here.
Will formication and itchy skin in perimenopause go away on their own? For many women, the frequency and intensity ease as hormones settle into a new, more stable baseline, particularly once you’re through the most turbulent, unpredictable stretch of the transition. That said, most women find real relief comes faster with targeted support — stabilizing blood sugar, rebuilding the skin barrier, and calming the nervous system — rather than simply waiting it out.
Can certain medications or supplements cause this instead of hormones? Yes, it’s worth reviewing with your doctor. Certain blood pressure medications, some antidepressants, iron supplements, and a handful of other common prescriptions can independently cause itching or altered skin sensation. If a new symptom started shortly after a new prescription or supplement, that timing is genuinely useful information to bring up.
Quick Check: Does This Sound Like You?
Read through this gently, as a pattern-recognition tool rather than a diagnostic checklist to measure yourself against.
- A crawling, tingling, or prickling sensation on your skin with nothing visibly there
- Itching that moves around your body, without a rash, bite marks, or clear trigger
- Symptoms that flare at night, or wake you up after you’ve fallen asleep
- A pattern that seems to intensify the week before your period, or around ovulation
- Itching or crawling sensations that show up alongside hot flashes, anxiety, or brain fog
- Skin that feels noticeably drier or thinner than it did a few years ago
- Symptoms that worsen after a poor night’s sleep, high stress, or a blood sugar crash
- No visible rash, hives, or skin change when you actually look at the area
If several of these sound familiar, that points toward a hormonal, histamine, or nerve-sensitivity pattern rather than a skin condition or infestation — but as the next section covers, there’s a short list of signs that genuinely do warrant a medical check, and it’s worth knowing them clearly.
Hormonal Formication vs. Something That Needs Medical Attention
This is the most important section of this article, and it deserves direct, specific language rather than vague reassurance, because vague reassurance is exactly what sends women into hours of anxious searching instead of getting real clarity.
Formication and itchy skin in perimenopause that are hormonally driven typically:
- Come and go, rather than being constant and unrelenting
- Move around the body without a fixed location
- Occur with no visible rash, hives, welts, or skin change
- Show up alongside other clear perimenopause symptoms — hot flashes, anxiety, irregular cycles, disrupted sleep
- Ease somewhat with cooling, moisturizing, antihistamines, or calming the nervous system
- Don’t come with weakness, numbness, or loss of coordination
- Don’t worsen progressively over weeks without any hormonal pattern to it
These are the signs that mean it’s time to see a doctor, not something to sit with indefinitely:
- A visible rash, hives, welts, or skin lesions accompanying the sensation
- Numbness, weakness, or loss of coordination in the affected area
- Symptoms confined to one very specific, consistent location rather than moving around
- Signs of an actual infestation — visible bites, tracks, or another person in the household with similar symptoms
- A new medication started around the same time symptoms began
- Symptoms that are severe, constant, and significantly disrupting daily function or sleep
- Any signs of thyroid dysfunction — unexplained weight change, heat or cold intolerance, hair thinning — alongside the itching
- A personal history of diabetes, kidney disease, or liver disease, which can also cause itching through separate mechanisms
Please don’t talk yourself out of getting this checked because you’re worried about sounding dramatic or being dismissed. A simple conversation with your doctor, potentially including a basic blood panel checking thyroid function, blood sugar, iron, and kidney and liver function, is a completely reasonable first step. For the significant majority of women experiencing this in the context of clear perimenopausal symptoms, these tests come back reassuringly normal — and that reassurance, backed by an actual check rather than assumption, is worth far more than any amount of anxious searching.
What Most Women Try First — and Why It Quietly Backfires
Scratching the sensation immediately, every time it appears. This is the most natural response in the world, but scratching triggers your skin to release even more histamine at the site, which can intensify the itch shortly after the initial relief fades — creating a cycle where scratching briefly helps and then makes the underlying sensitivity worse.
Assuming it’s an infestation and deep-cleaning everything obsessively. This instinct comes from a completely understandable place, but repeated deep-cleaning, especially with harsh detergents and hot water, often strips your skin’s already-compromised barrier further, making the nerve sensitivity underneath even more pronounced, not less.
Switching skincare products constantly, looking for the one that “fixes” it. Because the sensation isn’t primarily caused by a product reaction in most hormonal cases, constantly switching products often introduces new potential irritants faster than it removes them, and can leave your skin barrier in a near-permanent state of adjustment rather than settling.
Taking hot showers to “numb” the sensation. Heat can feel temporarily soothing, but hot water strips natural oils from your skin and dries it out further, which tends to worsen both the itch and the crawling sensation once the temporary numbing effect wears off.
Deciding, quietly, that something is deeply wrong without ever mentioning it to anyone. This is the belief sitting underneath so much of the distress here, and it’s the one most worth challenging directly — not by ignoring the symptom, but by naming it clearly to a doctor who can help rule things out, so you’re working from real information rather than a private, unspoken fear.
An Old Idea That Already Understood This Sensation
There’s a concept in Ayurveda, an ancient system of medicine, worth sitting with here, because it describes something strikingly close to what modern physiology is now confirming. Skin, in this tradition, is considered deeply connected to Vata — the body’s air and movement energy, responsible for everything related to nerve impulses, sensation, and the rapid, erratic movement of signals through the body. When Vata becomes aggravated, one of its most characteristic physical expressions is exactly this: unpredictable, moving sensations on the skin — tingling, crawling, prickling — alongside dryness, restlessness, and a nervous system that struggles to settle.
What’s notable here isn’t just that this pattern was named centuries before anyone could measure estrogen, histamine, or nerve conduction. It’s what this tradition understood about how to calm it. Vata, by nature, is dry, light, and erratic — like wind moving across a surface. And dryness responds to moisture and warmth, while erratic movement responds to steadiness and routine, not force. Warm oil applied to the skin, consistent daily rhythms, warm nourishing food, and calming the nervous system through breath and rest were the tools this tradition reached for — and remarkably, they map closely onto exactly what the research above points toward: rebuilding the skin barrier, calming nerve excitability, and giving an overactive nervous system consistent, steady signals rather than chaos.
What Actually Helps: A Real Plan for Formication and Itchy Skin in Perimenopause
1. Get it checked once, to rule out anything else — then let that clarity work for you
This is genuinely the highest-leverage step here, because so much of what makes this symptom distressing is the uncertainty layered on top of the physical sensation itself. A basic conversation with your doctor, along with bloodwork checking thyroid function, blood sugar, iron, and kidney and liver markers, gives you real information rather than guesswork. Once other causes are reasonably ruled out, you can start treating each flare as an uncomfortable but harmless hormonal event, rather than a mystery to solve every time it happens.
2. Rebuild your skin barrier, deliberately
Given how directly a thinning, drier skin barrier contributes to nerve irritation, this is addressing part of the actual mechanism, not just generic skincare advice. Look for fragrance-free, ceramide-rich moisturizers applied while your skin is still slightly damp, ideally right after a lukewarm — not hot — shower, to lock in moisture rather than fighting against it. Consistency matters more than any single product; applying a simple, barrier-supportive moisturizer twice daily tends to outperform an expensive product used sporadically.
3. Stabilize your blood sugar, meal by meal
Given how closely blood sugar swings track with adrenaline surges that increase nerve excitability, this is one of the most concrete, controllable levers available to you. Start your day with protein and fat rather than carbohydrates alone, avoid long gaps without eating, and pair caffeine with food rather than drinking it on an empty stomach — all of which blunt the spike-and-crash pattern that so often precedes a flare an hour or two later.
4. Support your histamine load through food
Since elevated histamine reactivity is a meaningful driver of unexplained itch during this transition, paying attention to histamine-heavy foods is worth trying, even briefly, to see if it makes a difference. Aged cheeses, cured meats, fermented foods, leftovers stored more than a day or two, alcohol — particularly red wine — and certain shellfish are common higher-histamine foods. This isn’t about permanent elimination; it’s about noticing, over a week or two, whether reducing these makes a real difference to how often flares show up.
It can also help to build more naturally low-histamine, anti-inflammatory foods into your day rather than only focusing on what to remove — fresh vegetables, most fruits, freshly cooked meat and fish, and gentle herbal teas like chamomile or peppermint. Cooking in batches but eating meals fresh rather than relying heavily on multi-day leftovers is a small, practical shift that many women find genuinely reduces flare frequency within a couple of weeks.
5. Rebuild your mineral and nutrient reserves
Given magnesium and B12’s direct role in nerve health and excitability, supporting your intake here addresses the actual mechanism rather than offering generic wellness advice. Magnesium-rich foods — leafy greens, pumpkin seeds, almonds, legumes — and B12 sources like eggs, fish, and fortified foods are a sensible foundation, and many women find a magnesium glycinate supplement in the evening genuinely helpful for both nerve calm and sleep quality, though it’s worth checking with your doctor first, especially alongside other medications.
6. Calm your nervous system, daily, not just during a flare
Given how directly anxiety and nervous system arousal increase skin nerve sensitivity, calming practices done consistently — rather than only reached for mid-flare — train your nervous system toward a steadier baseline overall. Slow, extended-exhale breathing is one of the most well-supported tools here: in for a count of four, hold briefly, out for a count of six to eight, done for even two to three minutes daily.
7. Protect your sleep like it’s part of your skin’s recovery, because it is
Given how much nighttime clustering ties into cortisol rhythm and reduced daytime distraction, treating consistent sleep and wake times as genuinely important matters here. A cooler bedroom, breathable bedding, and a short wind-down routine before bed all support both better sleep and a calmer nervous system heading into the night, when this symptom so often shows up.
8. Reduce, don’t eliminate, alcohol and hot showers
Both alcohol and very hot water directly aggravate the mechanisms behind this symptom — alcohol through histamine release and dehydration, hot water through stripping your skin’s protective barrier. Neither needs to disappear completely, but noticing, honestly, how flares track with either over a couple of weeks tends to be genuinely revealing.
9. Talk to your doctor specifically about the hormonal piece
Ask directly how estrogen’s fluctuation might be contributing to what you’re experiencing, rather than discussing itching or crawling sensations as an isolated, unexplained symptom. For some women, hormone therapy meaningfully reduces skin-related symptoms by smoothing out the very estrogen swings driving nerve and histamine sensitivity — a conversation worth having directly with someone who understands this transition, rather than being told generically to “moisturize more.”
10. Name the sensation when it happens, instead of chasing it
When a flare hits, try naming it internally: “this is a hormonal nerve signal, not a bug, not a danger — I’ve had this checked, and it will pass.” This isn’t about ignoring your body. It’s about interrupting the anxiety-sensation loop that keeps a brief, harmless flare feeling far more alarming and far longer-lasting than the physical sensation itself actually is.
When It’s Still Hard, Even When You’re Doing Everything Right
“I know it’s hormonal, and it still makes my skin crawl every single time.” That’s genuinely normal, and it doesn’t mean the knowledge isn’t working. Nervous system responses don’t disappear the moment you understand them intellectually — they ease gradually, with repetition, as your body slowly relearns that this sensation is safe. Give it time.
“Mine shows up for no reason at all, not even at night or around my cycle.” Some of the least predictable flares are the ones tied most closely to the invisible, moment-to-moment swings of estrogen and histamine themselves, without an obvious external trigger you can point to. That unpredictability is genuinely frustrating, but it’s still consistent with the hormonal pattern described here, not a sign something else is going on.
“I feel embarrassed even describing this to my doctor.” Please don’t let that stop you. This is a recognized, documented symptom of hormonal transition, and describing it clearly — “it feels like something is crawling on my skin, but there’s nothing there” — is exactly the kind of specific detail that helps a doctor understand and address it properly.
What Getting Better Actually Looks Like
Nobody’s nervous system recalibrates overnight, and hormone levels don’t stop fluctuating just because you’ve started taking better care of your skin and stress load. But the pattern does shift, meaningfully, over weeks and months. Flares tend to become less frequent and less intense. When they do happen, they tend to pass faster, because your nervous system isn’t adding a second wave of anxiety on top of the first hormonal signal. You start noticing a crawl or a prickle and, instead of your stomach dropping, you find yourself thinking, calmly, “there it is again” — and going back to what you were doing a minute later.
That’s really the goal here: not skin and nerves that never produce a sensation again, because hormonal fluctuation is simply part of this chapter, but a body — and a mind — that knows exactly what this sensation is, doesn’t spiral in response to it, and has real tools in place to calm it down when it happens.
Where to Go From Here
Formication and itchy skin in perimenopause are far more common than the silence around them suggests, and they are almost always driven by a real, traceable combination of nerve sensitivity, histamine reactivity, skin barrier changes, and hormonal fluctuation — not by anything crawling on you, and not by anything wrong with your mind. Once other causes are reasonably ruled out, this is something you can genuinely learn to manage with steady, consistent support, not something you have to quietly live in fear of.
Every piece covered here — blood sugar stability, skin barrier support, mineral levels, histamine load, sleep, nervous system regulation — is deeply individual, and it’s exactly the kind of thing that’s hard to piece together on your own from generic advice.
Want to understand what’s specifically driving your symptoms? Get your free Medhya Health Score and see exactly where your hormones, nervous system, gut, and skin stand right now — and get a personalized plan built around what your body actually needs.
Would it help to talk this through with someone who understands this transition? A one-on-one conversation with a Medhya Herbals practitioner can help — sometimes the most reassuring thing is simply having someone who’s seen this exact pattern in hundreds of other women sit with you in it directly.
That crawling feeling isn’t a sign your body is falling apart. It’s a hormonal season asking a little more of your nerves and your skin than they’re used to giving — and with the right support, that sensitivity is something you can genuinely calm back down.
This is general wellness information, not medical advice. If you experience a rash, hives, numbness, weakness, or a sensation confined to one specific area that doesn’t fit the pattern described above, please speak with a doctor promptly. Please also consult a doctor about any new or worsening skin symptoms, especially alongside a personal history of diabetes, thyroid, kidney, or liver conditions.
